��AV9�ck��O�]�ؖ��sc���͉� �;$���"a��;���q5BV�g�嬠S����I�:6�b��� h��uj3oQ�^��ҕ�*�����F��dV���k�����缊IFz0eTP�K�5q��ϥKY���4T żX�����4���2ո��m�Q�"z&{u�BӺ#H6 %PDF-1.6 %���� A toxic agent is anything that can produce an adverse biological effect. Classification of Toxic Substances Nature Chemical toxicants Biological toxins. possibility of deliberate release of pathogens or toxic agents into water intended for human consumption. ?�������LyZjɦ����CS�t�z8�x�܁b��S�!��ן;E���]�smȶ��׃�ܫ��|cY8Vݸ[���&=*1��_�'���S��< ��}˰g�v�������w�a���8�t����^2���9���K���b�p��s�q����)��D 8X�d� {� ��#�d5�ze�D�V�½T�\7O�u�� �Y�L��"���Ɗ�ێ㪌���c���l]��mĚ��;T�;�Z�����.���.���t�3b��1�^��F��Z)���������n�?R��9a����A,�)�Y�án�Gwk�� d��-? ^r�D%�����~�=M�+�M+����A�U�ߡ�`��BU�gD��Ӡ;��o9�Kx{�32�?��2-7��g�;�W��I)n,V�SÉ 1H$��{&z5a8�]� 1728 0 obj <>stream
We often rely on their physical form (e.g., liquid, vapor, solid, energetic, etc. ), size (e.g., nano-particle, respirable, micro, etc. �}�ԸezLܱ(s�Py� Ɂ���N�ȟ� ���l| A ;�-w��B�q9K���+�NY�o\�m�t�}f�� �Q���Ǯ0:��a�z�@V���D�V��)�P��h�7�9�F[�����0w:�ǎ5�X�myL(�ȉ�e�dU��2��4^u���9��֖�l���7P����v�>Y��j��q�;8#%5�q�=/��a9����︱HU��bzGD��A=1�)����`R����}�O;NJ�D6��E��d�����E)�nM�>�]��IE0a��?��y�9#�ۯ2��s��E�P����]��'�@{��v��b�1�� 0� �Q��%�TҖ�*f It deals with diagnosis and treatment of human poising. �1����1�6�ڰ�~��� Forensic Toxicology.

For example, toxic agents may be: Chemical (such as cyanide) Physical (such as radiation) Biological (such as snake venom) Figure 4. Cyanide is a chemical toxic agent (Image Source: NLM IRIS and ChemIDplus) Figure 5.

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Their use by humans plays an important role in determining their potential for health effects. Classification of Toxic Agents (2): Toxic substances are classified into the following: A. 2. Dr,)��~�)��Da�J佑��~�A��ɳM� ~��a �B}*����k#'�9��r��~���, �������Ү�UP X:�M���PE��R���F�3&3O[0��/|K_�#�����m��k SG�x-���U���Ѽ����t�����r���Jg�h� |֏���o�I:�z�ɖ��{?ɇ�i��VUM^&�5ʎ�Ö*5V��� |�ڭS2qē�Y�N릗�'�GA��6}��u,� 掤���?���!��7�MV � The Dutch Working conditions legislation stipulates that Annex III of EC Directive 2000/54/EC is the only authoritative list of classifications of biological agents in the Netherlands.

It deals with the evaluation of toxic substances present in biological specimen as well as in raw form or crude form. Pages 16 This preview shows page 3 - 7 out of 16 pages. 2. Heavy Metals Metals differ from other toxic substances in that they are neither created nor destroyed by humans. classification of biological agents is subjected to a comprehensive assessment, updated and harmonised. �`��#��צˢ�'��\(�R�p�zL��~�e~�"�H�ڶ����7vnlbs��0�n�� %PDF-1.7 %���� These classifications are based on the level of pathogenicity in healthy workers (i.e. T`�E��1t4�(CnA#�u� �m~PMX��nX�������O�Ņa��vJ6r`l��[-+��x��[���@�k�? ��J�تYm�k������7P�Yܬ�a��RqA�Xz�M}Z�,Q�b�?鱮0�xf�F�� ��i~F2δ�ڏ ���Y���TjR�=���&S� ��y{�$ö=5�-�6Rܙ�.ې�^�_����U�)��j�8����YΑ4����a܏'� D1��}숓mݣ�Җ5��%m��h�B̢����������(Ě��,I�K� It may be chemical, physical, or biological in form. Classification of Antineoplastic Agents by their Selective Toxicities toward Oxygenated and Hypoxie Tumor Cells1 Beverly A. Teicher,2 John S. Lazo, and Alan C. Salterelli Department ot Pharmacology and Developmental Therapeutics Program, Comprehensive Cancer Center, Yale University School of Medicine. V--��i�*!�Xi+ˁ�"�w��v�RC�.����[��v�MUX1��봧>�]���T ���k�~�q�8 r�2�$��KL��ũo,�m#��:1Έ|��=p|�$���6H���g�c5y���":�U��(�T���O�ͱ���ӕ}�X��M�e�J�

hތYˎ�6��AIER@�@&�L'H�ӻB/*@�y!hd7�C��u˶����h�\�a��� WY��������pmK�yɒ�j�/y��R�:�KЃgL��,�u������I������cU+6���R�*�ʰ��`* endstream endobj 516 0 obj <>stream ), or larger classifications (e.g., biological, mineral, etc.) (iv) This chapter includes both a basic and an extended system for classifying water-related disease, as well as discussing how attribution of cause, in terms of levels of likelihood, can be incorporated into the classification. 3. The Green Science Policy Institute coordinated a number of organizations (see below) to prioritize toxic chemicals and narrow it down to six classes of toxic substances – nasty chemicals explained. ����G�F�ڎ�8s Classification of toxic substances nature chemical.
515 0 obj <>stream �,�X� endstream endobj 517 0 obj <>stream Clinical Toxicology. Toxic agents, as they exist in the environment or following metabolism or binding, elicit their effects by either a genotoxic pathway (in which damage to DNA occurs) or a non-genotoxic pathway (in which DNA damage and mutagenesis need not occur). n�7�����8~Sn�C��5�Z��a�Վl�~ ��.�K���Gl��@����^� �4��~ And their evaluation involves identification and quantification of poisons using various analytical techniques. U�ch��x����(Bpvb�B%��!s�L�[��IMҙo�w�O�t�Ƶ������$����ʗ���6: endstream endobj 518 0 obj <>stream